Endocrine Abstracts

Introduction: The SARS-CoV 2 pandemic has resulted in millions of deaths worldwide. It has been suggested that sex steroids may be involved in the prognosis of the disease.Material and methods: Male patients diagnosed with SARS-CoV-2 infection admitted to the Marqués de Valdecilla University Hospital (Spain). Testosterone, androstenedione, estradiol, DHEA and DHEAS were determined in the first 24 h of admission and severe COVID was defined as mortal...

Introduction: Activation of the hypothalamic–pituitary–adrenal axis is critical for adaptation to stress and serious illness. The imbalance between anti-inflammatory activity of cortisol and proinflammatory activity of the androgens, dehydroepiandrosterone (DHEA) and dihydroepiandrosterone sulfate (DHEAS) can be an important predictor factor of mortality in sepsis.Material and methods: Patients diagnosed of severe sepsis or septic shock admitte...

Introduction: Smoking affects thyroid function, the magnitude and direction of the effect varies greatly with different studies. Less is known about the effect of smoking in thyroid function during pregnancy.Materials and methods: Healthy pregnant women with not known thyroid dysfunction were questioned about smoking habit in the first trimester of pregnancy. Blood samples for TSH, free T4 (fT4) and free T3 (fT3) were obtained in each trimester and for t...

Introduction: Gestational diabetes (GD) is one of the most common complications of pregnancy. Thyroid hormones play an important role in carbohydrate homeostasis, however, their influence on the risk of developing gestational diabetes has shown contradictory results.Objective: To explore whether variations in thyroid function parameters, within the thresholds of normality, can be associated with the risk of developing GD.Material a...